Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum. test 123
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum. Test for review
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.
We aim to make our process as easy as possible, and we’re happy to provide the following services to assist you:
Convenient text message reminders (opt-in required) to keep you up to date on the status of your prescription and refill schedule.
Shipment tracking so you know when to expect your DIACOMIT delivery.
Pharmacists on call 24/7 and translation services in 100+ languages to answer your questions or concerns about your child’s DIACOMIT prescription.
A dedicated Rare Care team that understands Dravet syndrome and DIACOMIT treatment so it can advocate for your child.
A team ready to resolve issues with insurance coverage and prior authorization, so you don’t have to.
Risks |
Recommendations |
---|---|
Phenylketonuria* *DIACOMIT for oral suspension contains phenylalanine, but DIACOMIT capsules do not. |
|
Decreased DIACOMIT concentrations due to induction-based interactions |
|
Effects on other drugs |
|
Neutropenia and thrombocytopenia |
|
Phenylketonuria* |
---|
*DIACOMIT for oral suspension contains phenylalanibe, but DIACOMIT capsules do not. |
Decreased DIACOMIT concentrations due to induction-based interactions |
|
Effects on other drugs |
|
Neutropenia and thrombocytopenia |
|
6 MONTHS TO 1 YEARa,b |
1 YEAR AND OLDER |
||
---|---|---|---|
BODY WEIGHT |
15 lb + |
15 lb – 22 lbb |
22 lb + |
STEP 1 Convert weight to kilograms |
15 lb = 7 kg |
18 lb = 8.2 kg |
30 lb = 13.6 kg |
STEP 2 Multiply by 50 mg |
7 kg x 50 mg = 350 mg/kg |
8.2 kg x 50 mg = 410 mg/kg |
13.6 kg x 50 mg = 680 mg/kg |
STEP 3 Round to nearest dose (250 mg increments) |
Round up to 500 mg |
Round up to 500 mg |
Round up to 750 mg |
STEP 4 Divide total into 2 or 3 daily doses |
Divide into 2 doses/day: 250 mg + 250 mg |
Divide into 2 doses/day: 250 mg + 250 mg |
Divide into 2 doses/day: 250 mg + 500 mg – OR – Divide into 3 doses/day: 250 mg + 250 mg + 250 mg |
6 MONTHS TO 1 YEARa,b |
|
---|---|
BODY WEIGHT |
15 lb + |
STEP 1 Convert weight to kilograms |
15 lb = 7 kg |
STEP 2 Multiply by 50 mg |
7 kg x 50 mg = 350 mg/kg |
STEP 3 Round to nearest dose (250 mg increments) |
Round up to 500 mg |
STEP 4 Divide total into 2 or 3 daily doses |
Divide into 2 doses/day: 250 mg + 250 mg |
1 YEAR AND OLDER |
|
BODY WEIGHT |
15 lb – 22 lbb |
STEP 1 Convert weight to kilograms |
18 lb = 8.2 kg |
STEP 2 Multiply by 50 mg |
8.2 kg x 50 mg = 410 mg/kg |
STEP 3 Round to nearest dose (250 mg increments) |
Round up to 500 mg |
STEP 4 Divide total into 2 or 3 daily doses |
Divide into 2 doses/day: 250 mg + 250 mg |
1 YEAR AND OLDER |
|
BODY WEIGHT |
22 lb + |
STEP 1 Convert weight to kilograms |
30 lb = 13.6 kg |
STEP 2 Multiply by 50 mg |
13.6 kg x 50 mg = 680 mg/kg |
STEP 3 Round to nearest dose (250 mg increments) |
Round up to 750 mg |
STEP 4 Divide total into 2 or 3 daily doses |
Divide into 2 doses/day: 250 mg + 500 mg – OR – Divide into 3 doses/day: 250 mg + 250 mg + 250 mg |
aDosing frequency should not exceed twice daily to limit free water administration.
bDosing frequency should not exceed twice daily to avoid overexposures.
OVERALL SEIZURE FREQUENCY |
STP + CLB (n=35) |
STP + CLB + VPA (n=48) |
---|---|---|
Marked reduction |
17 (35%) |
17 (35%) |
Mild reduction |
13 (27%) |
13 (27%) |
No Change |
16 (33%) |
16 (33%) |
Mild worsening |
2 (4%) |
2 (4%) |
Marked worsening |
0 (0%) |
0 (0%) |
STP + CLB (n=35) |
|
---|---|
Marked reduction |
17 (35%) |
Mild reduction |
13 (27%) |
No Change |
16 (33%) |
Mild worsening |
2 (4%) |
Marked worsening |
0 (0%) |
STP + CLB + VPA (n=48) |
|
Marked reduction |
17 (35%) |
Mild reduction |
13 (27%) |
No Change |
16 (33%) |
Mild worsening |
2 (4%) |
Marked worsening |
0 (0%) |
STP = stiripentol; CLB = clobazam; VPA = valproate
Two strengths
Two dosing forms
G40.83: Dravet syndrome, polymorphic epilepsy in infancy (PMEI) or severe myoclonic epilepsy in infancy (SMEI)
G40.833: Dravet syndrome, intractable, with status epilepticus
G40.834: Dravet syndrome, intractable, without status epilepticus
A completed Patient Enrollment Form.
A copy of your patient’s insurance card (front and back).
A prescription with clear dosing and titration instructions.
List of your patient’s current medications.
Your patient’s medical records.
Tip: Ensure your patient’s chart has a Dravet diagnosis code:
Work with the specialty pharmacy to complete and submit required payer forms.
If needed, complete a letter of medical necessity.
If needed, complete a letter of appeal.
Notify your patient or their caregiver that the specialty pharmacy will reach out to coordinate shipment and delivery.
Save the Biocodex By Your Side number: 833-248-0467.
DIACOMIT’s has 25 years of clinical experience and extensive data collection and analysis.7,36,37
Download this guide for information on studies illustrating DIACOMIT’s efficacy and safety profile.
Download GuideKeep this list handy to check the documented and potential drug interactions with DIACOMIT.
Download CardReview this summary of a study that investigated the perceived efficacy of DIACOMIT.
Download Efficacy PosterReview this summary of a study that explored DIACOMIT dosing practices.
Download Dosing PosterShare this brochure with caregivers of patients with Dravet syndrome to help them learn about DIACOMIT.
Download Caregiver's GuideI gotta do what I dang-ol’ gotta do, man.
-Boomhauer
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